Ontology highlight
ABSTRACT:
SUBMITTER: Illingworth RS
PROVIDER: S-EPMC4333374 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Illingworth Robert S RS Gruenewald-Schneider Ulrike U De Sousa Dina D Webb Shaun S Merusi Cara C Kerr Alastair R W AR James Keith D KD Smith Colin C Walker Robert R Andrews Robert R Bird Adrian P AP
Nucleic acids research 20150108 2
The possibility that alterations in DNA methylation are mechanistic drivers of development, aging and susceptibility to disease is widely acknowledged, but evidence remains patchy or inconclusive. Of particular interest in this regard is the brain, where it has been reported that DNA methylation impacts on neuronal activity, learning and memory, drug addiction and neurodegeneration. Until recently, however, little was known about the 'landscape' of the human brain methylome. Here we assay 1.9 mi ...[more]