Foxq2 determines blue cone identity in zebrafish.
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ABSTRACT:
SUBMITTER: Ogawa Y
PROVIDER: S-EPMC8494292 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Publications
Foxq2 determines blue cone identity in zebrafish.
Ogawa Yohey Y Shiraki Tomoya T Fukada Yoshitaka Y Kojima Daisuke D
Science advances 20211006 41
Most vertebrate lineages retain a tetrachromatic visual system, which is supported by a functional combination of spectrally distinct multiple cone photoreceptors, ultraviolet (UV), blue, green, and red cones. The blue cone identity is ensured by selective expression of blue (<i>sws2</i>) opsin, and the mechanism is poorly understood because <i>sws2</i> gene has been lost in mammalian species such as mouse, whose visual system has been extensively studied. Here, we pursued loss-of-function studi ...[more]
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