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Molecular evidence of mother-to-infant transmission of hepatitis G virus among women without known risk factors for parenteral infections.


ABSTRACT: Hepatitis G virus (HGV) RNA was detected in 18 of 133 pregnant women from Tanzania without known risk factors for HGV infection and in 7 of 18 children born to HGV RNA-positive mothers. Molecular evidence of mother-to-infant transmission was obtained only for three of seven children. HGV RNA was also detected in 4 of 42 children born to non-HGV-infected women. Thus, mechanisms other than materno-filial may play an important role in HGV transmission during early childhood.

SUBMITTER: Menendez C 

PROVIDER: S-EPMC85152 | biostudies-literature | 1999 Jul

REPOSITORIES: biostudies-literature

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Molecular evidence of mother-to-infant transmission of hepatitis G virus among women without known risk factors for parenteral infections.

Menéndez C C   Sánchez-Tapias J M JM   Alonso P L PL   Giménez-Barcons M M   Kahigwa E E   Aponte J J JJ   Mshinda H H   Navia M M MM   Jiménez de Anta M T MT   Rodés J J   Saiz J C JC  

Journal of clinical microbiology 19990701 7


Hepatitis G virus (HGV) RNA was detected in 18 of 133 pregnant women from Tanzania without known risk factors for HGV infection and in 7 of 18 children born to HGV RNA-positive mothers. Molecular evidence of mother-to-infant transmission was obtained only for three of seven children. HGV RNA was also detected in 4 of 42 children born to non-HGV-infected women. Thus, mechanisms other than materno-filial may play an important role in HGV transmission during early childhood. ...[more]

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