Ontology highlight
ABSTRACT:
SUBMITTER: Yang H
PROVIDER: S-EPMC8515396 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
ACS omega 20210928 40
A novel metal catalyst-free and environmentally friendly method for the regioselective iodination of imidazo[1,2-α]pyridines at their C3 position is disclosed, which has a wide substrate scope and could be sustainable. This reaction proceeds through ultrasound acceleration in the presence of a green alcohol solvent. Compared with a conventional heating system, the reaction efficiency and the rate are significantly improved and the iodine atom economy is maximized using ultrasound techniques. ...[more]