Dataset Information

High-Intensity Interval Training for Knee Osteoarthritis: A Pilot Study.

ABSTRACT:

Objective

To assess the feasibility and changes in outcomes of a 12-week high-intensity interval training (HIIT) program in individuals with symptomatic knee osteoarthritis (OA).

Methods

The single-arm trial included 29 participants (mean ± SD age 63 ± 7 years; 66% women; 66% obese). Measures of participant flow, adherence, and tolerability were collected. Pain, function, and balance were assessed at baseline, 6 weeks, and 12 weeks using the Western Ontario and McMaster Universities Osteoarthritis Index, 20-m fast-paced walk test, 30-second chair-stand test, stair-climb test, timed up and go test, and single leg stance. Cardiorespiratory fitness, strength, and body composition were evaluated using peak oxygen consumption (VO₂ peak), isometric knee extensor/flexor strength, and dual-energy x-ray absorptiometry, respectively. HIIT was completed two times/week (cycling or treadmill) and consisted of 10 repetitions of 1-minute bouts at 90% VO₂ peak, with 1-minute rest periods. Separate multivariable-adjusted linear mixed models were fit for each outcome with fixed effects of time, age, sex, body mass index, and random effects of baseline values to estimate mean changes and 95% confidence intervals (CIs) between baseline and 12-week assessments.

Results

Recruitment aligned with the anticipated enrollment rate, adherence was 70%, and no adverse events were reported. At 12 weeks, improvements were observed for most outcomes, with notable mean changes for the 20-m fast-paced walk (-1.13 [95% CI -1.61 to -0.64] seconds), 30-second chair-stand (2.6 [1.8-3.4] stands), and VO₂ peak (0.14 [0.03-0.24] liters/minute).

Conclusion

In this 12-week pilot study, HIIT improved multiple aspects of health in individuals with knee OA; larger studies are needed.

SUBMITTER: Golightly YM

PROVIDER: S-EPMC8516105 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

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Publications

High-Intensity Interval Training for Knee Osteoarthritis: A Pilot Study.

Golightly Yvonne M YM Smith-Ryan Abbie E AE Blue Malia N M MNM Alvarez Carolina C Allen Kelli D KD Nelson Amanda E AE

ACR open rheumatology 20210807 10

<h4>Objective</h4>To assess the feasibility and changes in outcomes of a 12-week high-intensity interval training (HIIT) program in individuals with symptomatic knee osteoarthritis (OA).<h4>Methods</h4>The single-arm trial included 29 participants (mean ± SD age 63 ± 7 years; 66% women; 66% obese). Measures of participant flow, adherence, and tolerability were collected. Pain, function, and balance were assessed at baseline, 6 weeks, and 12 weeks using the Western Ontario and McMaster Universiti ...[more]

PMID: 34363745

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Dataset Information

High-Intensity Interval Training for Knee Osteoarthritis: A Pilot Study.

Objective

Methods

Results

Conclusion

Publications

High-Intensity Interval Training for Knee Osteoarthritis: A Pilot Study.

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