Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC8529050 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Li Xiaoying X Yang Yueyao Y Huang Qian Q Deng Yu Y Guo Fukun F Wang Gang G Liu Ming M
Frontiers in cell and developmental biology 20211007
Immune checkpoint inhibitors (ICIs) have changed the landscape of cancer treatment and are emerging as promising curative treatments in different type of cancers. However, only a small proportion of patients have benefited from ICIs and there is an urgent need to find robust biomarkers for individualized immunotherapy and to explore the causes of immunotherapy resistance. In this article, we review the roles of immune cells in the tumor microenvironment (TME) and discuss the effects of ICIs on t ...[more]