Validation of a visual analog scale for assessing cough severity in patients with chronic cough.

ABSTRACT:

Introduction

Patients with chronic cough experience considerable burden. The cough severity visual analog scale (VAS) records patients' assessment of cough severity on a 100-mm linear scale ranging from "no cough" (0 mm) to "worst cough" (100 mm). Although cough severity scales are widely used in clinical practice and research, their use in patients with refractory or unexplained chronic cough has not been formally validated.

Methods

This analysis includes data from a phase 2b randomized controlled trial of the P2X3-receptor antagonist gefapixant for treatment of refractory or unexplained chronic cough (NCT02612610). Cough severity VAS scores were assessed at baseline and Weeks 4, 8, and 12. The cough severity VAS was validated using several outcomes, including the Cough Sev

SUBMITTER: Martin Nguyen A 

PROVIDER: S-EPMC8552382 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature