Proper Immune Response Depends on Early Exposure to Gut Microbiota in Broiler Chicks.

ABSTRACT: The successional changes in the early intestinal microbiota occur concomitantly with the development, expansion, and education of the mucosal immune system. Although great attention of researchers has been focused on understanding the linkage between microbiota and immune functions, many essential details of the symbiotic relationship between the intestinal pioneer microbiota and the avian immune system remain to be discovered. This study was conducted to understand the impact of different early life intestinal colonizers on innate and adaptive immune processes in chicks and further identify immune-associated proteins expressed in the intestinal tissue. To accomplish it, we performed an in ovo application of two apathogenic Enterobacteriaceae isolates and lactic acid bacteria

SUBMITTER: Rodrigues DR 

PROVIDER: S-EPMC8554228 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature