Ontology highlight
ABSTRACT:
SUBMITTER: Jo H
PROVIDER: S-EPMC8569116 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Jo Hyelim H Kim Taemook T Chun Yujin Y Jung Inkyung I Lee Daeyoup D
Nature communications 20211104 1
We herein employ in situ Hi-C with an auxin-inducible degron (AID) system to examine the effect of chromatin remodeling on 3D genome organization in yeast. Eight selected ATP-dependent chromatin remodelers representing various subfamilies contribute to 3D genome organization differently. Among the studied remodelers, the temporary depletions of Chd1p, Swr1p, and Sth1p (a catalytic subunit of the Remodeling the Structure of Chromatin [RSC] complex) cause the most significant defects in intra-chro ...[more]