Ontology highlight
ABSTRACT:
SUBMITTER: Lambert JP
PROVIDER: S-EPMC3018163 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Lambert Jean-Philippe JP Fillingham Jeffrey J Siahbazi Mojgan M Greenblatt Jack J Baetz Kristin K Figeys Daniel D
Molecular systems biology 20101201
We previously reported a novel affinity purification (AP) method termed modified chromatin immunopurification (mChIP), which permits selective enrichment of DNA-bound proteins along with their associated protein network. In this study, we report a large-scale study of the protein network of 102 chromatin-related proteins from budding yeast that were analyzed by mChIP coupled to mass spectrometry. This effort resulted in the detection of 2966 high confidence protein associations with 724 distinct ...[more]