Association Between an Increase in Serum Sodium and In-Hospital Mortality in Critically Ill Patients.

ABSTRACT:

Objectives

In critically ill patients, dysnatremia is common, and in these patients, in-hospital mortality is higher. It remains unknown whether changes of serum sodium after ICU admission affect mortality, especially whether normalization of mild hyponatremia improves survival.

Design

Retrospective cohort study.

Setting

Ten Dutch ICUs between January 2011 and April 2017.

Patients

Adult patients were included if at least one serum sodium measurement within 24 hours of ICU admission and at least one serum sodium measurement 24-48 hours after ICU admission were available.

Interventions

None.

Measurements and main results

A logistic regression model adjusted for age, sex, and Acute Physiology and Chronic Health Evaluation-IV-predicted mortality was u

SUBMITTER: Grim CCA 

PROVIDER: S-EPMC8594512 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature