Ontology highlight
ABSTRACT:
SUBMITTER: Mateu-Regue A
PROVIDER: S-EPMC8599746 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Mateu-Regué Àngels À Christiansen Jan J Bagger Frederik Otzen FO Hellriegel Christian C Nielsen Finn Cilius FC
Nucleic acids research 20211101 20
Understanding the mRNA life cycle requires information about the dynamics and macromolecular composition and stoichiometry of mRNPs. Fluorescence correlation and cross-correlation spectroscopy (FCS and FCCS) are appealing technologies to study these macromolecular structures because they have single molecule sensitivity and readily provide information about their molecular composition and dynamics. Here, we demonstrate how FCS can be exploited to study cytoplasmic mRNPs with high accuracy and re ...[more]