Ontology highlight
ABSTRACT:
SUBMITTER: Perez-Hernandez N
PROVIDER: S-EPMC8615378 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Pérez-Hernández Nonanzit N Posadas-Sánchez Rosalinda R Vargas-Alarcón Gilberto G Hernández-Germán Lizet Paola LP Borgonio-Cuadra Verónica Marusa VM Rodríguez-Pérez José Manuel JM
Biomedicines 20211102 11
Osteopontin (<i>OPN</i>) is considered a clinical predictor of cardiovascular disease. We aimed to evaluate the association of the <i>OPN</i> gene polymorphisms rs2728127 and rs11730582 with the development of premature coronary artery disease (pCAD), cardiovascular risk factors, and cardiometabolic parameters. We evaluated 1142 patients with pCAD and 1073 controls. Both polymorphisms were determined by Taqman assays. Similar allele and genotype frequencies were observed in both groups; addition ...[more]