Association between psychotropic drug use and handgrip strength in older hospitalized patients.

ABSTRACT:

Purpose

Handgrip strength is an indicator of frailty and longevity in older adults. The association between psychotropic drug use and handgrip strength in older hospitalized patients was investigated in this study.

Methods

A total of 488 patients were included in this retrospective cross-sectional study, 333 women and 155 men, from two different cohorts of older (mean age 84 years) hospitalized in-patients. We used multiple linear regression models to explore the association between psychotropic drug use and handgrip strength. We adjusted for factors known to affect handgrip strength: Age, gender, body mass index (BMI) and comorbidity (Charlson comorbidity index).

Results

Both unadjusted and adjusted analyses showed that psychotropic drug use was associated with handg

SUBMITTER: Sandvik MK 

PROVIDER: S-EPMC8626357 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature