Association between handgrip strength, balance, and knee flexion/extension strength in older adults.
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ABSTRACT:
SUBMITTER: Alonso AC
PROVIDER: S-EPMC5983424 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Association between handgrip strength, balance, and knee flexion/extension strength in older adults.
Alonso Angelica Castilho AC Ribeiro Samia Maria SM Luna Natália Mariana Silva NMS Peterson Mark D MD Bocalini Danilo Sales DS Serra Marcos Maurício MM Brech Guilherme Carlos GC Greve Julia Maria D'Andréa JMD Garcez-Leme Luiz Eugênio LE
PloS one 20180601 6
The objective of the study was to examine the association between handgrip strength (HGS), knee flexion and extension strength, and static and dynamic balance in older women. One hundred and ten women with a mean age of 67.4±5.9 years were assessed for dynamic postural balance using the Time Up & Go Test (TUG) with and without cognitive tasks. Semi-static balance was assessed by means of a force platform; knee flexor and extensor muscle strength was calculated using an isokinetic dynamometer; an ...[more]
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Project description:PurposeHandgrip strength is an indicator of frailty and longevity in older adults. The association between psychotropic drug use and handgrip strength in older hospitalized patients was investigated in this study.MethodsA total of 488 patients were included in this retrospective cross-sectional study, 333 women and 155 men, from two different cohorts of older (mean age 84 years) hospitalized in-patients. We used multiple linear regression models to explore the association between psychotropic drug use and handgrip strength. We adjusted for factors known to affect handgrip strength: Age, gender, body mass index (BMI) and comorbidity (Charlson comorbidity index).ResultsBoth unadjusted and adjusted analyses showed that psychotropic drug use was associated with handgrip strength (β = - 0.183, p < 0.0001). The relationship was of a linear character, with no clear threshold value, but with the greatest reduction in handgrip strength between zero and two psychotropic drugs.ConclusionAn increasing number of psychotropic drugs were significantly associated with reduced handgrip strength in a linearly pattern. Hence, it is timely to question the guided threshold value of avoidance of three or more psychotropic drugs in older people. Psychotropic drug use should be kept as low as possible in treatment of older patients.
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