MiR-183-5p Aggravates Breast Cancer Development via Mediation of RGS2.
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ABSTRACT:
SUBMITTER: Wu C
PROVIDER: S-EPMC8627563 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
miR-183-5p Aggravates Breast Cancer Development via Mediation of RGS2.
Wu Chihua C Tuo Youlin Y Hu Gang G Luo Jing J
Computational and mathematical methods in medicine 20211120
This study mainly explores how miR-183-5p pertains to breast cancer (BC) development. Functional assays were employed to test impacts of miR-183-5p in this cancer. Targeting between RGS2 and miR-183-5p was examined with dual-luciferase assay, and how their interaction pertains to cancer progression was further unraveled. miR-183-5p level was noticeably high in cancer tissue/cells. Overexpressing miR-183-5p could remarkably deteriorate cancer progression. The regulatory gene RGS2 levels was marke ...[more]
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