Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC8646714 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Wang Jue J Zhang Yongjing Y Hu Shiling S Bai Haoyun H Xue Zhuoyin Z Liu Yanhong Y Ma Weina W
Journal of biochemical and molecular toxicology 20211110 2
The outbreak of coronavirus disease 2019 (COVID-19) has induced a large number of deaths worldwide. Angiotensin-converting enzyme 2 (ACE2) is the entry receptor for the 2019 novel coronavirus (2019-nCoV) to infect the host cells. Therefore, ACE2 may be an important target for the prevention and treatment of COVID-19. The aim of this study was to investigate the inhibition effect of valaciclovir hydrochloride (VACV), zidovudine (ZDV), saquinavir (SQV), and efavirenz (EFV) on 2019-nCoV infection. ...[more]