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Normal imaging findings after aortic valve implantation on ¹⁸F-Fluorodeoxyglucose positron emission tomography with computed tomography.

ABSTRACT:

Background

To determine the normal perivalvular ¹⁸F-Fluorodeoxyglucose (¹⁸F-FDG) uptake on positron emission tomography (PET) with computed tomography (CT) within one year after aortic prosthetic heart valve (PHV) implantation.

Methods

Patients with uncomplicated aortic PHV implantation were prospectively included and underwent ¹⁸F-FDG PET/CT at either 5 (± 1) weeks (group 1), 12 (± 2) weeks (group 2) or 52 (± 8) weeks (group 3) after implantation. ¹⁸F-FDG uptake around the PHV was scored qualitatively (none/low/intermediate/high) and quantitatively by measuring the maximum Standardized Uptake Value (SUV_max) and target to background ratio (SUV_ratio).

Results

In total, 37 patients (group 1: n = 12, group 2: n = 12, group 3: n = 13) (mean age 66 ± 8 years) were prospectively included. Perivalvular ¹⁸F-FDG uptake was low (8/12 (67%)) and intermediate (4/12 (33%)) in group 1, low (7/12 (58%)) and intermediate (5/12 (42%)) in group 2, and low (8/13 (62%)) and intermediate (5/13 (38%)) in group 3 (P = 0.91). SUV_max was 4.1 ± 0.7, 4.6 ± 0.9 and 3.8 ± 0.7 (mean ± SD, P = 0.08), and SUV_ratio was 2.0 [1.9 to 2.2], 2.0 [1.8 to 2.6], and 1.9 [1.7 to 2.0] (median [IQR], P = 0.81) for groups 1, 2, and 3, respectively.

Conclusion

Non-infected aortic PHV have similar low to intermediate perivalvular ¹⁸F-FDG uptake with similar SUV_max and SUV_ratio at 5, 12, and 52 weeks after implantation.

SUBMITTER: Wahadat AR

PROVIDER: S-EPMC8648629 | biostudies-literature |

REPOSITORIES: biostudies-literature

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