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Normal imaging findings after aortic valve implantation on 18F-Fluorodeoxyglucose positron emission tomography with computed tomography.


ABSTRACT:

Background

To determine the normal perivalvular 18F-Fluorodeoxyglucose (18F-FDG) uptake on positron emission tomography (PET) with computed tomography (CT) within one year after aortic prosthetic heart valve (PHV) implantation.

Methods

Patients with uncomplicated aortic PHV implantation were prospectively included and underwent 18F-FDG PET/CT at either 5 (± 1) weeks (group 1), 12 (± 2) weeks (group 2) or 52 (± 8) weeks (group 3) after implantation. 18F-FDG uptake around the PHV was scored qualitatively (none/low/intermediate/high) and quantitatively by measuring the maximum Standardized Uptake Value (SUVmax) and target to background ratio (SUVratio).

Results

In total, 37 patients (group 1: n = 12, group 2: n = 12, group 3: n = 13) (mean age 66 ± 8 years) were prospectively included. Perivalvular 18F-FDG uptake was low (8/12 (67%)) and intermediate (4/12 (33%)) in group 1, low (7/12 (58%)) and intermediate (5/12 (42%)) in group 2, and low (8/13 (62%)) and intermediate (5/13 (38%)) in group 3 (P = 0.91). SUVmax was 4.1 ± 0.7, 4.6 ± 0.9 and 3.8 ± 0.7 (mean ± SD, P = 0.08), and SUVratio was 2.0 [1.9 to 2.2], 2.0 [1.8 to 2.6], and 1.9 [1.7 to 2.0] (median [IQR], P = 0.81) for groups 1, 2, and 3, respectively.

Conclusion

Non-infected aortic PHV have similar low to intermediate perivalvular 18F-FDG uptake with similar SUVmax and SUVratio at 5, 12, and 52 weeks after implantation.

SUBMITTER: Wahadat AR 

PROVIDER: S-EPMC8648629 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

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Publications

Normal imaging findings after aortic valve implantation on <sup>18</sup>F-Fluorodeoxyglucose positron emission tomography with computed tomography.

Wahadat Ali R AR   Tanis Wilco W   Scholtens Asbjørn M AM   Bekker Margreet M   Graven Laura H LH   Swart Laurens E LE   den Harder Annemarie M AM   Lam Marnix G E H MGEH   de Heer Linda M LM   Roos-Hesselink Jolien W JW   Budde Ricardo P J RPJ  

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20200123 5


<h4>Background</h4>To determine the normal perivalvular <sup>18</sup>F-Fluorodeoxyglucose (<sup>18</sup>F-FDG) uptake on positron emission tomography (PET) with computed tomography (CT) within one year after aortic prosthetic heart valve (PHV) implantation.<h4>Methods</h4>Patients with uncomplicated aortic PHV implantation were prospectively included and underwent <sup>18</sup>F-FDG PET/CT at either 5 (± 1) weeks (group 1), 12 (± 2) weeks (group 2) or 52 (± 8) weeks (group 3) after implantation.  ...[more]

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