Ontology highlight
ABSTRACT:
SUBMITTER: Yue R
PROVIDER: S-EPMC8689006 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Yue Rongcai R Liu Haiping H Huang Yaxin Y Wang Jing J Shi Dongmei D Su Yanping Y Luo Yufei Y Cai Ping P Jin Guilin G Yu Changxi C
Frontiers in pharmacology 20211207
<i>Gelsemium elegans</i> (<i>G. elegans</i>) Benth., recognized as a toxic plant, has been used as traditional Chinese medicine for the treatment of neuropathic pain and cancer for many years. In the present study, we aim to obtain the anti-tumor effects of alkaloids of <i>G. elegans</i> and their active components in hepatocellular carcinoma (HCC) and the potential mechanism was also further investigated. We demonstrated that sempervirine induced HCC cells apoptosis and the apoptosis was associ ...[more]