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Visible light-driven Giese reaction with alkyl tosylates catalysed by nucleophilic cobalt.

ABSTRACT: The scope of the Giese reaction is expanded using readily available alkyl tosylates as substrates and nucleophilic cobalt(i) catalysts under visible-light irradiation. The reaction proceeds preferentially with less bulky primary alkyl tosylates. This unique reactivity enables the regio-selective Giese reaction of polyol derivatives.

SUBMITTER: Komeyama K

PROVIDER: S-EPMC8693991 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Visible light-driven Giese reaction with alkyl tosylates catalysed by nucleophilic cobalt.

Komeyama Kimihiro K Michiyuki Takuya T Teshima Yoshikazu Y Osaka Itaru I

RSC advances 20210118 6

The scope of the Giese reaction is expanded using readily available alkyl tosylates as substrates and nucleophilic cobalt(i) catalysts under visible-light irradiation. The reaction proceeds preferentially with less bulky primary alkyl tosylates. This unique reactivity enables the regio-selective Giese reaction of polyol derivatives. ...[more]

PMID: 35424301

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