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A short, versatile route towards benzothiadiazinyl radicals.


ABSTRACT: A family of substituted 1,2,4-benzothiadiazine 1-chlorides have been prepared by treatment of N-arylamidines in neat thionyl chloride at reflux. The S(iv) 1-chlorides are readily reduced under mild conditions to persistent 1,2,4-benzothiadiazinyl radicals which have been characterised by EPR spectroscopy and cyclic voltammetry. Crystallographic studies on isolated radicals indicate that the radicals dimerise via pancake bonding in the solid-state, resulting in spin-pairing and net diamagnetism.

SUBMITTER: Borys AM 

PROVIDER: S-EPMC8694340 | biostudies-literature |

REPOSITORIES: biostudies-literature

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