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ABSTRACT:
SUBMITTER: Hosaka T
PROVIDER: S-EPMC8710789 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Hosaka Tetsuya T Suzuki Fumitaka F Kobayashi Mariko M Fujiyama Shunichiro S Kawamura Yusuke Y Sezaki Hitomi H Akuta Norio N Kobayashi Masahiro M Suzuki Yoshiyuki Y Saitoh Satoshi S Arase Yasuji Y Ikeda Kenji K Kumada Hiromitsu H
Hepatology communications 20210916 1
Serum hepatitis B core-related antigen (HBcrAg) and surface antigen (HBsAg) are surrogate markers of intrahepatic covalently closed circular DNA. The measurement range of the current HBcrAg assay is relatively narrow. Thus, we examined the potential of HBcrAg and HBsAg measured by ultrasensitive assays for predicting hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B treated with entecavir (ETV). We conducted a retrospective cohort study of 180 patients who received ...[more]