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A prognostic approach on a case of pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia with monosomy-7.


ABSTRACT: In this work, we present the first case of a Ph-positive ALL Moroccan girl with t(9;22)(q34;q11) and monosomy-7. She was diagnosed with Ph-positive ALL based on bone marrow examination, immunophenotyping, and cytogenetic analysis. She relapsed after treatment with the persistence of the Ph chromosome and the appearance of a monosomy-7.

SUBMITTER: Skhoun H 

PROVIDER: S-EPMC8710846 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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A prognostic approach on a case of pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia with monosomy-7.

Skhoun Hanaa H   Khattab Mohammed M   Belkhayat Aziza A   Takki Chebihi Zahra Z   Dakka Nadia N   El Baghdadi Jamila J  

Clinical case reports 20211226 12


In this work, we present the first case of a Ph-positive ALL Moroccan girl with <i>t</i>(9;22)(q34;q11) and monosomy-7. She was diagnosed with Ph-positive ALL based on bone marrow examination, immunophenotyping, and cytogenetic analysis. She relapsed after treatment with the persistence of the Ph chromosome and the appearance of a monosomy-7. ...[more]

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