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Computational Fluid Dynamics Modeling of Liver Radioembolization: A Review.


ABSTRACT: Yttrium-90 radioembolization (RE) is a widely used transcatheter intraarterial therapy for patients with unresectable liver cancer. In the last decade, computer simulations of hepatic artery hemodynamics during RE have been performed with the aim of better understanding and improving the therapy. In this review, we introduce the concept of computational fluid dynamics (CFD) modeling with a clinical perspective and we review the CFD models used to study RE from the fluid mechanics point of view. Finally, we show what CFD simulations have taught us about the hemodynamics during RE, the current capabilities of CFD simulations of RE, and we suggest some future perspectives.

SUBMITTER: Aramburu J 

PROVIDER: S-EPMC8716346 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

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Computational Fluid Dynamics Modeling of Liver Radioembolization: A Review.

Aramburu Jorge J   Antón Raúl R   Rodríguez-Fraile Macarena M   Sangro Bruno B   Bilbao José Ignacio JI  

Cardiovascular and interventional radiology 20210913 1


Yttrium-90 radioembolization (RE) is a widely used transcatheter intraarterial therapy for patients with unresectable liver cancer. In the last decade, computer simulations of hepatic artery hemodynamics during RE have been performed with the aim of better understanding and improving the therapy. In this review, we introduce the concept of computational fluid dynamics (CFD) modeling with a clinical perspective and we review the CFD models used to study RE from the fluid mechanics point of view.  ...[more]

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