Ontology highlight
ABSTRACT:
SUBMITTER: Ben Khelil M
PROVIDER: S-EPMC8750687 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Ben Khelil Myriam M Godet Yann Y Abdeljaoued Syrine S Borg Christophe C Adotévi Olivier O Loyon Romain R
Cancers 20220105 1
Over the past decades, CD4<sup>+</sup> T cells have been considered as a supporting actor in the fields of cancer immunotherapy. Until recently, accumulating evidence has demonstrated the critical role of CD4<sup>+</sup> T cells during antitumor immunity. CD4<sup>+</sup> T cells can either suppress or promote the antitumor cytotoxic CD8<sup>+</sup> T cell responses, either in secondary lymphoid organs or in the tumor. In this review, we provide an overview of the multifaceted role of different C ...[more]