Ontology highlight
ABSTRACT:
SUBMITTER: Hennings AC
PROVIDER: S-EPMC8792329 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Hennings Augustin C AC McClay Mason M Drew Michael R MR Lewis-Peacock Jarrod A JA Dunsmoor Joseph E JE
Current biology : CB 20211122 2
Neurobiological research in rodents has revealed that competing experiences of fear and extinction are stored as distinct memory traces in the brain. This divided organization is adaptive for mitigating overgeneralization of fear to related stimuli that are learned to be safe while also maintaining threat associations for unsafe stimuli. The mechanisms involved in organizing these competing memories in the human brain remain unclear. Here, we used a hybrid form of Pavlovian conditioning with an ...[more]