Secondary Structure of Subgenomic RNA M of SARS-CoV-2.
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ABSTRACT:
SUBMITTER: Soszynska-Jozwiak M
PROVIDER: S-EPMC8878378 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Publications
Secondary Structure of Subgenomic RNA M of SARS-CoV-2.
Soszynska-Jozwiak Marta M Ruszkowska Agnieszka A Kierzek Ryszard R O'Leary Collin A CA Moss Walter N WN Kierzek Elzbieta E
Viruses 20220204 2
SARS-CoV-2 belongs to the <i>Coronavirinae</i> family. Like other coronaviruses, SARS-CoV-2 is enveloped and possesses a positive-sense, single-stranded RNA genome of ~30 kb. Genomic RNA is used as the template for replication and transcription. During these processes, positive-sense genomic RNA (gRNA) and subgenomic RNAs (sgRNAs) are created. Several studies presented the importance of the genomic RNA secondary structure in SARS-CoV-2 replication. However, the structure of sgRNAs has remained l ...[more]
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