Dataset Information
HOMELETTE: a unified interface to homology modelling software.
Ontology highlight
ABSTRACT: Summary
Homology modelling, the technique of generating models of 3D protein structures based on experimental structures from related proteins, has become increasingly popular over the years. An abundance of different tools for model generation and model evaluation is available from various research groups. We present HOMELETTE, an interface which implements a unified programmatic access to these tools. This allows for the assemble of custom pipelines from pre- or self-implemented building blocks.Availability and implementation
HOMELETTE is implemented in Python, compatible with version 3.6 and newer. It is distributed under the MIT license. Documentation and tutorials are available at Read the Docs (https://homelette.readthedocs.io/). The latest version of HOMELETTE is available on PyPI (https://pypi.org/project/homelette/) and GitHub (https://github.com/PhilippJunk/homelette). A full installation of the latest version of HOMELETTE with all dependencies is also available as a Docker container (https://hub.docker.com/r/philippjunk/homelette_template).Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Junk P
PROVIDER: S-EPMC8896651 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Publications
HOMELETTE: a unified interface to homology modelling software.
Bioinformatics (Oxford, England) 20220301 6
<h4>Summary</h4>Homology modelling, the technique of generating models of 3D protein structures based on experimental structures from related proteins, has become increasingly popular over the years. An abundance of different tools for model generation and model evaluation is available from various research groups. We present HOMELETTE, an interface which implements a unified programmatic access to these tools. This allows for the assemble of custom pipelines from pre- or self-implemented buildi ...[more]