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Aclidinium bromide for stable chronic obstructive pulmonary disease.


ABSTRACT:

SUBMITTER: Ni H 

PROVIDER: S-EPMC8922974 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

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Aclidinium bromide for stable chronic obstructive pulmonary disease.

Ni Han H   Soe Zay Z   Moe Soe S  

The Cochrane database of systematic reviews 20140919 9


<h4>Background</h4>Bronchodilators are the mainstay for symptom relief in the management of stable chronic obstructive pulmonary disease (COPD). Aclidinium bromide is a new long-acting muscarinic antagonist (LAMA) that differs from tiotropium by its higher selectivity for M3 muscarinic receptors with a faster onset of action. However, the duration of action of aclidinium is shorter than for tiotropium. It has been approved as maintenance therapy for stable, moderate to severe COPD, but its effic  ...[more]

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