Ontology highlight
ABSTRACT:
SUBMITTER: Ni H
PROVIDER: S-EPMC8922974 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
The Cochrane database of systematic reviews 20140919 9
<h4>Background</h4>Bronchodilators are the mainstay for symptom relief in the management of stable chronic obstructive pulmonary disease (COPD). Aclidinium bromide is a new long-acting muscarinic antagonist (LAMA) that differs from tiotropium by its higher selectivity for M3 muscarinic receptors with a faster onset of action. However, the duration of action of aclidinium is shorter than for tiotropium. It has been approved as maintenance therapy for stable, moderate to severe COPD, but its effic ...[more]