Purging of deleterious burden in the endangered Iberian lynx.
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ABSTRACT:
SUBMITTER: Kleinman-Ruiz D
PROVIDER: S-EPMC8931242 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Publications
Purging of deleterious burden in the endangered Iberian lynx.
Kleinman-Ruiz Daniel D Lucena-Perez Maria M Villanueva Beatriz B Fernández Jesús J Saveljev Alexander P AP Ratkiewicz Mirosław M Schmidt Krzysztof K Galtier Nicolas N García-Dorado Aurora A Godoy José A JA
Proceedings of the National Academy of Sciences of the United States of America 20220301 11
SignificanceThe dynamics of deleterious variation under contrasting demographic scenarios remain poorly understood in spite of their relevance in evolutionary and conservation terms. Here we apply a genomic approach to study differences in the burden of deleterious alleles between the endangered Iberian lynx (<i>Lynx pardinus</i>) and the widespread Eurasian lynx (<i>Lynx lynx</i>). Our analysis unveils a significantly lower deleterious burden in the former species that should be ascribed to gen ...[more]
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