TIC236 gain-of-function mutations unveil the link between plastid division and plastid protein import.
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SUBMITTER: Fang J
PROVIDER: S-EPMC8931380 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
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<i>TIC236</i> gain-of-function mutations unveil the link between plastid division and plastid protein import.
Fang Jun J Li Bingqi B Chen Lih-Jen LJ Dogra Vivek V Luo Shengji S Wu Wangpin W Wang Pengcheng P Hwang Inhwan I Li Hsou-Min HM Kim Chanhong C
Proceedings of the National Academy of Sciences of the United States of America 20220311 11
SignificanceAlthough plastid division is critical for plant development, how components of the plastid division machinery (PDM) are imported into plastids remains unexplored. A forward genetic screen to identify suppressors of a <i>crumpled leaf</i> (<i>crl</i>) mutant deficient in plastid division led us to find dominant gain-of-function (GF) mutations in <i>TIC236</i>, which significantly increases the import of PDM components and completely rescues <i>crl</i> phenotypes. The defective plastid ...[more]
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