Ontology highlight
ABSTRACT:
SUBMITTER: Pellicer-Valero OJ
PROVIDER: S-EPMC8945373 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Pellicer-Valero Óscar J ÓJ Massaro Giampiero A GA Casanova Alfredo G AG Paniagua-Sancho María M Fuentes-Calvo Isabel I Harvat Mykola M Martín-Guerrero José D JD Martínez-Salgado Carlos C López-Hernández Francisco J FJ
Biomedicines 20220305 3
Glomerular filtration is a pivotal process of renal physiology, and its alterations are a central pathological event in acute kidney injury and chronic kidney disease. Creatinine clearance (ClCr), a standard method for glomerular filtration rate (GFR) measurement, requires a long and tedious procedure of timed (usually 24 h) urine collection. We have developed a neural network (NN)-based calculator of rat ClCr from plasma creatinine (pCr) and body weight. For this purpose, matched pCr, weight, a ...[more]