Ontology highlight
ABSTRACT:
SUBMITTER: Zhou X
PROVIDER: S-EPMC8990409 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Zhou Xu X Zhou Yu Y Shao Weiqing W Hong Liang L Lu Ming M Zhu Wenwei W
Journal of Cancer 20220314 6
Intrahepatic cholangiocarcinoma (ICC) is the most common malignant bile duct tumor in the liver and the second most common primary liver cancer with increasing morbidity and poor prognosis. Metabolic aberration plays key roles in cancer progression. As a key metabolic intermediate, acetyl-CoA accumulation shows close association with cancer metastasis. However, the role of acetyl-CoA metabolic aberration in ICC is still undetermined. Here, by investigating tissue samples from ICC patients and IC ...[more]