Ontology highlight
ABSTRACT:
SUBMITTER: Ren X
PROVIDER: S-EPMC9007680 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Ren Xudong X Zhou Yu Y Luo Yunling Y Wang Chaoqun C Pan Anna A Ju Yanqin Y Sun Haoting H Lin Zhifei Z Hu Beiyuan B Sun Guangzheng G Zhu Wenwei W Hong Liang L
Gastroenterology research and practice 20220406
Interleukin-6 (IL-6), an important inflammatory cytokine, is a key factor regulating cancer metastasis. Cancer cells can modulate their tumorigenic abilities by sorting specific microRNAs (miRNAs) as exosomes into the tumor microenvironment. The relationship between IL-6 and exosomal miRNAs related to hepatocellular carcinoma (HCC) metastasis remains to be elucidated. We examined the metastatic ability of HCC cells after IL-6 treatment and found that miR-133a-3p was sorted into exosomes after IL ...[more]