Ontology highlight
ABSTRACT:
SUBMITTER: Villa L
PROVIDER: S-EPMC90180 | biostudies-literature | 2000 Oct
REPOSITORIES: biostudies-literature
Villa L L Pezzella C C Tosini F F Visca P P Petrucca A A Carattoli A A
Antimicrobial agents and chemotherapy 20001001 10
A conjugative IncL/M plasmid (pSEM) conferring resistance to gentamicin, amikacin, kanamycin, sulfonamides, and expanded-spectrum cephalosporins was found in pathogenic strains of Salmonella enterica serotype Typhimurium. Resistance to aminoglycosides was encoded by a sul1-type class 1 integron (In-t3). An extended-spectrum beta-lactamase gene, bla(SHV-5), was identified 3. 5 kb downstream of the integrase (intI1) gene of In-t3. Nucleotide sequence analysis of the 5.3-kb bla(SHV-5)-In-t3 region ...[more]