Target-Specific Exosome Isolation through Aptamer-Based Microfluidics.
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ABSTRACT:
SUBMITTER: Zhou Z
PROVIDER: S-EPMC9027373 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Publications
Target-Specific Exosome Isolation through Aptamer-Based Microfluidics.
Zhou Zixuan Z Chen Yan Y Qian Xiang X
Biosensors 20220418 4
Exosomes (30-100 nm in diameter) are a group of cell-derived membrane vesicles, packaged as valuable cargo with lipid, proteins, and genetic materials from their parent cells. With the increasing interest in exosomes for diagnostic and therapeutic applications, the rapid isolation of pure exosome populations has become a hot topic. In this paper, we propose modified microchannels with aptamer in a microfluidics system for rapid and efficient isolation of exosomes by targeting exosome-carrying CD ...[more]
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