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Photo-triggered cargo release from liposome chlorin e6-bearing pullulan hybrid nanoparticles via membrane permeabilization.

ABSTRACT: A liposome chlorin e6-bearing pullulan nanogel hybrid was prepared as a light-triggered payload release platform. The current system enabled manipulation of the release profile of model drugs encapsulated by liposomes. Gelatin hydrogels that comprised hybrid nanoparticles could successfully control the delivery of cargo molecules to human mesenchymal stem cells with light stimuli without injury to the cells.

SUBMITTER: Kawasaki R

PROVIDER: S-EPMC9043425 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Photo-triggered cargo release from liposome chlorin e6-bearing pullulan hybrid nanoparticles <i>via</i> membrane permeabilization.

Kawasaki Riku R Ohdake Reo R Eto Takuro T Yamana Keita K Nakaya Toshimi T Ishida Takenori T Kuroda Akio A Ikeda Atsushi A

RSC advances 20211112 58

A liposome chlorin e6-bearing pullulan nanogel hybrid was prepared as a light-triggered payload release platform. The current system enabled manipulation of the release profile of model drugs encapsulated by liposomes. Gelatin hydrogels that comprised hybrid nanoparticles could successfully control the delivery of cargo molecules to human mesenchymal stem cells with light stimuli without injury to the cells. ...[more]

PMID: 35494347

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