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Highly sensitive non-enzymatic hydrogen peroxide monitoring platform based on nanoporous gold via a modified solid-phase reaction method.

ABSTRACT: In this work, nanoporous gold (NPG) fabricated using a modified solid-phase reaction method was developed as an electrocatalyst for the nonenzymatic detection of hydrogen peroxide (H₂O₂). The NPG morphology and structure were characterized by scanning electron microscopy and high-resolution transmission electron microscopy. The fabricated NPG exhibited a nanoporous framework with numerous structural defects. The NPG-based amperometric H₂O₂ sensor had a good selectivity, reproducibility, and low detection limit (0.3 μM) under near physiological conditions (pH = 7.4). The sensitivities of this sensor over concentration ranges of 0.002-5 mM and 5-37.5 mM were 159 and 64 μA mM^-1 cm^-2, respectively. These results indicate that the developed NPG is a promising material for the electrochemical sensing of H₂O₂.

SUBMITTER: Yang Z

PROVIDER: S-EPMC9043567 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Highly sensitive non-enzymatic hydrogen peroxide monitoring platform based on nanoporous gold via a modified solid-phase reaction method.

Yang Zhipeng Z Li Jun J Liu Panmei P Zhang An A Wang Jing J Huang Yuan Y Wang Jiangyong J Wang Zumin Z

RSC advances 20211116 58

In this work, nanoporous gold (NPG) fabricated using a modified solid-phase reaction method was developed as an electrocatalyst for the nonenzymatic detection of hydrogen peroxide (H2O2). The NPG morphology and structure were characterized by scanning electron microscopy and high-resolution transmission electron microscopy. The fabricated NPG exhibited a nanoporous framework with numerous structural defects. The NPG-based amperometric H2O2 sensor had a ...[more]

PMID: 35494343

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