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ABSTRACT: Purpose
To develop a convolutional neural network (CNN) for the robust and fast correction of velocity aliasing in 4D-flow MRI.Methods
This study included 667 adult subjects with aortic 4D-flow MRI data with existing velocity aliasing (n = 362) and no velocity aliasing (n = 305). Additionally, 10 controls received back-to-back 4D-flow scans with systemically varied velocity-encoding sensitivity (vencs) at 60, 100, and 175 cm/s. The no-aliasing data sets were used to simulate velocity aliasing by reducing the venc to 40%-70% of the original, alongside a ground truth locating all aliased voxels (153 training, 152 testing). The 152 simulated and 362 existing aliasing data sets were used for testing and compared with a conventional velocity antialiasing algorithm. Dice scores were calculated to quantify CNN performance. For controls, the venc 175-cm/s scans were used as the ground truth and compared with the CNN-corrected venc 60 and 100 cm/s data sets RESULTS: The CNN required 176 ± 30 s to perform compared with 162 ± 14 s for the conventional algorithm. The CNN showed excellent performance for the simulated data compared with the conventional algorithm (median range of Dice scores CNN: [0.89-0.99], conventional algorithm: [0.84-0.94], p < 0.001, across all simulated vencs) and detected more aliased voxels in existing velocity aliasing data sets (median detected CNN: 159 voxels [31-605], conventional algorithm: 65 [7-417], p < 0.001). For controls, the CNN showed Dice scores of 0.98 [0.95-0.99] and 0.96 [0.87-0.99] for venc = 60 cm/s and 100 cm/s, respectively, while flow comparisons showed moderate-excellent agreement.Conclusion
Deep learning enabled fast and robust velocity anti-aliasing in 4D-flow MRI.
SUBMITTER: Berhane H
PROVIDER: S-EPMC9050855 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Berhane Haben H Scott Michael B MB Barker Alex J AJ McCarthy Patrick P Avery Ryan R Allen Brad B Malaisrie Chris C Robinson Joshua D JD Rigsby Cynthia K CK Markl Michael M
Magnetic resonance in medicine 20220405 1
<h4>Purpose</h4>To develop a convolutional neural network (CNN) for the robust and fast correction of velocity aliasing in 4D-flow MRI.<h4>Methods</h4>This study included 667 adult subjects with aortic 4D-flow MRI data with existing velocity aliasing (n = 362) and no velocity aliasing (n = 305). Additionally, 10 controls received back-to-back 4D-flow scans with systemically varied velocity-encoding sensitivity (vencs) at 60, 100, and 175 cm/s. The no-aliasing data sets were used to simulate velo ...[more]