Ontology highlight
ABSTRACT:
SUBMITTER: Sharhan O
PROVIDER: S-EPMC9090615 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Sharhan Olla O Heidelberg Thorsten T Hashim Najiahah Mohd NM Salman Abbas Abdulameer AA Ali Hapipah Mohd HM Jayash Soher Nagi SN
RSC advances 20181120 68
A new series of acridine based imidazolium salts was synthesized and evaluated for <i>in vitro</i> cytotoxicity against human cancer cell lines by an MTT assay. The synthesis applied a coupling of imidazoles with 9-chloroacridines, which originated from an Ullmann condensation of a 2-chloro-benzoic acid with an aniline. The target compounds were obtained in high yields. The DPPH assay indicated considerable antioxidant activity for target compounds with simple and short alkyl chains on the imida ...[more]