Disruption of the Trichoderma reesei gul1 gene stimulates hyphal branching and reduces broth viscosity in cellulase production.
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ABSTRACT:
SUBMITTER: Zhao Q
PROVIDER: S-EPMC9113457 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
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Disruption of the Trichoderma reesei gul1 gene stimulates hyphal branching and reduces broth viscosity in cellulase production.
Zhao Qinqin Q Liu Qin Q Wang Qi Q Qin Yuqi Y Zhong Yaohua Y Gao Liwei L Liu Guodong G Qu Yinbo Y
Journal of industrial microbiology & biotechnology 20210401 1-2
Hyphal morphology is considered to have a close relationship with the production level of secreted proteins by filamentous fungi. In this study, the gul1 gene, which encodes a putative mRNA-binding protein, was disrupted in cellulase-producing fungus Trichoderma reesei. The hyphae of Δgul1 strain produced more lateral branches than the parent strain. Under the condition for cellulase production, disruption of gul1 resulted in smaller mycelial clumps and significantly lower viscosity of fermentat ...[more]
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