Ontology highlight
ABSTRACT:
SUBMITTER: Shu H
PROVIDER: S-EPMC9138358 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Shu Huiling H Zhang Rongxin R Xiao Ke K Yang Jing J Sun Xiao X
Biomolecules 20220429 5
G-quadruplexes (G4s) are non-canonical secondary nucleic acid structures. Sequences with the potential to form G4s are abundant in regulatory regions of the genome including telomeres, promoters and 5' non-coding regions, indicating they fulfill important genome regulatory functions. Generally, G4s perform various biological functions by interacting with proteins. In recent years, an increasing number of G-quadruplex-binding proteins have been identified with biochemical experiments. G4-binding ...[more]