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Updates in IDH-Wildtype Glioblastoma.


ABSTRACT: Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021 WHO CNS5 classification has further stressed the importance of molecular signatures in diagnosis although therapeutic breakthroughs are still lacking. In this review article, updates on the current and novel therapies in IDH-wildtype GBM will be discussed.

SUBMITTER: Melhem JM 

PROVIDER: S-EPMC9154038 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Updates in IDH-Wildtype Glioblastoma.

Melhem Jawad M JM   Detsky Jay J   Lim-Fat Mary Jane MJ   Perry James R JR  

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20220531 6


Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021 WHO CNS5 classification has further stressed the importance of molecular signatures in diagnosis although therapeutic breakthroughs are still lacking. In this review article, updates on the current and novel therapies in IDH-wildtype GBM will be discussed. ...[more]

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