Ontology highlight
ABSTRACT:
SUBMITTER: Gielkens MM
PROVIDER: S-EPMC91575 | biostudies-literature | 1999 Oct
REPOSITORIES: biostudies-literature
Gielkens M M MM Dekkers E E Visser J J de Graaff L H LH
Applied and environmental microbiology 19991001 10
Two cellobiohydrolase-encoding genes, cbhA and cbhB, have been isolated from the filamentous fungus Aspergillus niger. The deduced amino acid sequence shows that CbhB has a modular structure consisting of a fungus-type cellulose-binding domain (CBD) and a catalytic domain separated by a Pro/Ser/Thr-rich linker peptide. CbhA consists only of a catalytic domain and lacks a CBD and linker peptide. Both proteins are homologous to fungal cellobiohydrolases in family 7 of the glycosyl hydrolases. Nort ...[more]