Janus kinase inhibitors for the treatment of COVID-19.
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ABSTRACT:
SUBMITTER: Kramer A
PROVIDER: S-EPMC9190191 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Publications
Janus kinase inhibitors for the treatment of COVID-19.
Kramer Andre A Prinz Carolin C Fichtner Falk F Fischer Anna-Lena AL Thieme Volker V Grundeis Felicitas F Spagl Manuel M Seeber Christian C Piechotta Vanessa V Metzendorf Maria-Inti MI Golinski Martin M Moerer Onnen O Stephani Caspar C Mikolajewska Agata A Kluge Stefan S Stegemann Miriam M Laudi Sven S Skoetz Nicole N
The Cochrane database of systematic reviews 20220613
<h4>Background</h4>With potential antiviral and anti-inflammatory properties, Janus kinase (JAK) inhibitors represent a potential treatment for symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. They may modulate the exuberant immune response to SARS-CoV-2 infection. Furthermore, a direct antiviral effect has been described. An understanding of the current evidence regarding the efficacy and safety of JAK inhibitors as a treatment for coronavirus disease 2019 (CO ...[more]
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