Ontology highlight
ABSTRACT:
SUBMITTER: Katki HA
PROVIDER: S-EPMC9190212 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Katki Hormuzd A HA Bebu Ionut I
Journal of the Royal Statistical Society. Series A, (Statistics in Society) 20210323 3
Decision Curve Analysis (DCA) is a popular approach for assessing biomarkers and risk models, but does not require costs and thus cannot identify optimal risk thresholds for actions. Full decision analyses can identify optimal thresholds, but typically used methods are complex and often difficult to understand. We develop a simple framework to calculate the Incremental Net Benefit for a single-time screen as a function of costs (for tests and treatments) and effectiveness (life-years gained). We ...[more]