Dataset Information

Cardiovascular Risk Factors and Clinical Outcomes among Patients Hospitalized with COVID-19: Findings from the World Heart Federation COVID-19 Study.

ABSTRACT:

Background and aims

Limited data exist on the cardiovascular manifestations and risk factors in people hospitalized with COVID-19 from low- and middle-income countries. This study aims to describe cardiovascular risk factors, clinical manifestations, and outcomes among patients hospitalized with COVID-19 in low, lower-middle, upper-middle- and high-income countries (LIC, LMIC, UMIC, HIC).

Methods

Through a prospective cohort study, data on demographics and pre-existing conditions at hospital admission, clinical outcomes at hospital discharge (death, major adverse cardiovascular events (MACE), renal failure, neurological events, and pulmonary outcomes), 30-day vital status, and re-hospitalization were collected. Descriptive analyses and multivariable log-binomial regression models, adjusted for age, sex, ethnicity/income groups, and clinical characteristics, were performed.

Results

Forty hospitals from 23 countries recruited 5,313 patients with COVID-19 (LIC = 7.1%, LMIC = 47.5%, UMIC = 19.6%, HIC = 25.7%). Mean age was 57.0 (±16.1) years, male 59.4%, pre-existing conditions included: hypertension 47.3%, diabetes 32.0%, coronary heart disease 10.9%, and heart failure 5.5%. The most frequently reported cardiovascular discharge diagnoses were cardiac arrest (5.5%), acute heart failure (3.8%), and myocardial infarction (1.6%). The rate of in-hospital deaths was 12.9% (N = 683), and post-discharge 30 days deaths was 2.6% (N = 118) (overall death rate 15.1%). The most common causes of death were respiratory failure (39.3%) and sudden cardiac death (20.0%). The predictors of overall mortality included older age (≥60 years), male sex, pre-existing coronary heart disease, renal disease, diabetes, ICU admission, oxygen therapy, and higher respiratory rates (p < 0.001 for each). Compared to Caucasians, Asians, Blacks, and Hispanics had almost 2-4 times higher risk of death. Further, patients from LIC, LMIC, UMIC versus. HIC had 2-3 times increased risk of death.

Conclusions

The LIC, LMIC, and UMIC's have sparse data on COVID-19. We provide robust evidence on COVID-19 outcomes in these countries. This study can help guide future health care planning for the pandemic globally.

SUBMITTER: Prabhakaran D

PROVIDER: S-EPMC9205371 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Publications

Cardiovascular Risk Factors and Clinical Outcomes among Patients Hospitalized with COVID-19: Findings from the World Heart Federation COVID-19 Study.

Prabhakaran Dorairaj D Singh Kavita K Kondal Dimple D Raspail Lana L Mohan Bishav B Kato Toru T Sarrafzadegan Nizal N Talukder Shamim Hayder SH Akter Shahin S Amin Mohammad Robed MR Goma Fastone F Gomez-Mesa Juan J Ntusi Ntobeko N Inofomoh Francisca F Deora Surender S Philippov Evgenii E Svarovskaya Alla A Konradi Alexandra A Puentes Aurelio A Ogah Okechukwu S OS Stanetic Bojan B Issa Aurora A Thienemann Friedrich F Juzar Dafsah D Zaidel Ezequiel E Sheikh Sana S Ojji Dike D Lam Carolyn S P CSP Ge Junbo J Banerjee Amitava A Newby L Kristin LK Ribeiro Antonio Luiz P ALP Gidding Samuel S Pinto Fausto F Perel Pablo P Sliwa Karen K

Global heart 20220615 1

<h4>Background and aims</h4>Limited data exist on the cardiovascular manifestations and risk factors in people hospitalized with COVID-19 from low- and middle-income countries. This study aims to describe cardiovascular risk factors, clinical manifestations, and outcomes among patients hospitalized with COVID-19 in low, lower-middle, upper-middle- and high-income countries (LIC, LMIC, UMIC, HIC).<h4>Methods</h4>Through a prospective cohort study, data on demographics and pre-existing conditions ...[more]

PMID: 35837356

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Dataset Information

Cardiovascular Risk Factors and Clinical Outcomes among Patients Hospitalized with COVID-19: Findings from the World Heart Federation COVID-19 Study.

Background and aims

Methods

Results

Conclusions

Publications

Cardiovascular Risk Factors and Clinical Outcomes among Patients Hospitalized with COVID-19: Findings from the World Heart Federation COVID-19 Study.

Similar Datasets

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