Cortisol in relation to problematic eating behaviours, adiposity and symptom profiles in Major Depressive Disorder.

ABSTRACT:

Aims

Major Depressive Disorder (MDD) is associated with an increased risk of chronic disease related to weight gain, problematic eating behaviours and neuroendocrine changes. MDD is frequently associated with altered hypothalamic-pituitary-adrenal axis activity and cortisol secretion, where cortisol has been implicated in regulating energy balance, food intake and depressogenic weight changes. However, little research has examined the relationships between cortisol, adiposity and depressogenic problematic eating behaviours.

Method

Plasma cortisol concentrations were compared between 37 participants with MDD reporting appetite/weight loss, 43 participants with MDD reporting appetite/weight gain, and 60 healthy controls, by sex. Associations between cortisol, indices of adipos

SUBMITTER: Mills JG 

PROVIDER: S-EPMC9216397 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature