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Investigation on the elemental profiles of lip cosmetic products: Concentrations, distribution and assessment of potential carcinogenic and non-carcinogenic human health risk for consumer safety.

ABSTRACT: Metal contamination of lip care products can cause potential adverse effects for consumers, hence assessment of human health risks associated with the consumption of these products is inevitable to ensure the consumers' safety. In the presented study, the profiles of 18 elements in 37 of the most popular lip cosmetic products, of various types and brands, sold in the Saudi Arabian markets, were investigated and their associated potential carcinogenic and non-carcinogenic human health risks were assessed. The metal concentrations were determined using inductively coupled plasma mass spectrometry preceded by microwave digestion for sample preparation. In general, the concentrations of the investigated metals were lower than the safe permissible limits with the exception of Cd, Pb and Hg. The results found that Cd was regarded as the primary metal contaminant present in the analyzed lip products contributing to 66.3% of the total determined carcinogenic health risk. Overall, however it was observed that there was no significant non-carcinogenic (hazard index < 1) or carcinogenic (Risk_T < 10^-4) health risks associated with the use of the investigated lip products. Although all the calculated values in this study were within the acceptable limits, special attention should be taken in order to prioritize minimizing the trace metals in lip products, especially for Cd, Pb, Ti and Hg. This study could provide vital data needed to ascertain the degree to which heavy metal exposure through cosmetics is prevalent.

SUBMITTER: Shaaban H

PROVIDER: S-EPMC9257854 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Project description:Fragranced consumer products, such as cleaning supplies, air fresheners, and personal care products, can emit a range of air pollutants and trigger adverse health effects. This study investigates the prevalence and types of effects of fragranced products on asthmatics in the American population. Using a nationally representative sample (n?=?1137), data were collected with an on-line survey of adults in the USA, of which 26.8% responded as being medically diagnosed with asthma or an asthma-like condition. Results indicate that 64.3% of asthmatics report one or more types of adverse health effects from fragranced products, including respiratory problems (43.3%), migraine headaches (28.2%), and asthma attacks (27.9%). Overall, asthmatics were more likely to experience adverse health effects from fragranced products than non-asthmatics (prevalence odds ratio [POR] 5.76; 95% confidence interval [CI] 4.34-7.64). In particular, 41.0% of asthmatics report health problems from air fresheners or deodorizers, 28.9% from scented laundry products coming from a dryer vent, 42.3% from being in a room cleaned with scented products, and 46.2% from being near someone wearing a fragranced product. Of these effects, 62.8% would be considered disabling under the definition of the Americans with Disabilities Act. Yet 99.3% of asthmatics are exposed to fragranced products at least once a week. Also, 36.7% cannot use a public restroom if it has an air freshener or deodorizer, and 39.7% would enter a business but then leave as quickly as possible due to air fresheners or some fragranced product. Further, 35.4% of asthmatics have lost workdays or a job, in the past year, due to fragranced product exposure in the workplace. More than twice as many asthmatics would prefer that workplaces, health care facilities and health care professionals, hotels, and airplanes were fragrance-free rather than fragranced. Results from this study point to relatively simple and cost-effective ways to reduce exposure to air pollutants and health risks for asthmatics by reducing their exposure to fragranced products.

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Investigation on the elemental profiles of lip cosmetic products: Concentrations, distribution and assessment of potential carcinogenic and non-carcinogenic human health risk for consumer safety.

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