Ontology highlight
ABSTRACT:
SUBMITTER: Moi D
PROVIDER: S-EPMC9259645 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Moi David D Nishio Shunsuke S Li Xiaohui X Valansi Clari C Langleib Mauricio M Brukman Nicolas G NG Flyak Kateryna K Dessimoz Christophe C de Sanctis Daniele D Tunyasuvunakool Kathryn K Jumper John J Graña Martin M Romero Héctor H Aguilar Pablo S PS Jovine Luca L Podbilewicz Benjamin B
Nature communications 20220706 1
Sexual reproduction consists of genome reduction by meiosis and subsequent gamete fusion. The presence of genes homologous to eukaryotic meiotic genes in archaea and bacteria suggests that DNA repair mechanisms evolved towards meiotic recombination. However, fusogenic proteins resembling those found in gamete fusion in eukaryotes have so far not been found in prokaryotes. Here, we identify archaeal proteins that are homologs of fusexins, a superfamily of fusogens that mediate eukaryotic gamete a ...[more]